Warnings/PrecautionsDo not take Revatio if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket). Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking Revatio with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack.
Before taking Revatio, tell your doctor if you are allergic to any drugs, or if you have:
- heart disease or heart rhythm problems;
- a recent history (in the past 6 months) of a heart attack, stroke, or heart rhythm disorder;
- congestive heart failure;
- high or low blood pressure;
- coronary artery disease;
- liver disease;
- kidney disease;
- a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
- a bleeding disorder such as hemophilia;
- a stomach ulcer;
- retinitis pigmentosa (an inherited condition of the eye);
- a physical deformity of the penis (such as Peyronie's disease); or
- if you have been told you should not have sexual intercourse for health reasons.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take Revatio.
Revatio can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Revatio, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. It is not clear whether Revatio is the actual cause of vision loss.
Do not use Revatio without telling your doctor if you are pregnant or plan to become pregnant during treatment. It is not known if Revatio passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
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