General Health

Purinethol (Mercaptopurine)

Purinethol is used to treat leukemia. It is also used for pediatric non-Hodgkin's lymphoma, polycythemia vera, and psoriatic arthritis. This medication may also be used for inflammatory bowel disease.

This is a potent medication. Take it exactly as prescribed. Unless your doctor instructs you otherwise, drink plenty of fluids to avoid dehydration. Contact your doctor if you vomit shortly after taking your dose.

Mercaptopurine belongs to the group of cancer-fighting medicines known as antineoplastics, and specifically to the group of antineoplastics known as antimetabolites. Mercaptopurine fights cancer by preventing the growth of cancer cells, which eventually results in their destruction. Mercaptopurine is usually used to treat leukemia.

Take the dose as soon as remembered but if it is almost time to take your next dose, skip the missed dose and resume your regular dosing schedule. Do not double dose to catch up.

Store at room temperature away from sunlight and moisture.

Tell your doctor your medical history, especially of: kidney disease, liver disease, any infections, previous anti-cancer treatment, blood disorders, recent exposure to chickenpox, any allergies you may have. This medication can lower your body's ability to fight an infection. Notify your doctor if you develop any signs of infection such as fever, sore throat, rash or chills. Avoid touching your eyes or inside your nose without first washing your hands. Use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports in order to lower the chance of getting cut, bruised or injured. Do not have immunizations/vaccinations without consent of your doctor and avoid contact with people who have recently received oral polio vaccine. Drinking alcohol may increase the possibility of developing stomach (GI tract) irritation or liver damage. Contraceptive (birth control) measures are recommended for use in men and women while taking this medication. This medication is not recommended for use during pregnancy. Consult your doctor. It is not known if this drug passes into breast milk. Because this is a powerful drug and may affect a nursing infant, consult your doctor before breast-feeding.